The general field of the research in our lab is the development of novel systems for medical imaging. Of particular interest are imaging systems utilizing x-rays (i.e. radiography, x-ray tomosynthesis, x-ray computed tomography (CT)) and/or nuclear medicine (i.e. scintigraphy, gamma ray emission tomosynthesis, single photon emission computed tomography (SPECT), and positron emission computed tomography (PET)). In recent years we have focused on the development of multimodal hybrid systems that integrate anatomic and functional image sets. Current application areas include breast cancer detection and characterization, intraoperative image guidance, and pre-clinical in vivo imaging.