Most of the information encoded within the genome of a human or of a bacteria is ultimately expressed as the linear sequence of amino acids in an expressed protein. This sequence determines, within the environment of that organism, the structure(s) of that protein. In turn, this structure(s) determines the interactions and functions of the protein. As we learn more of how sequences determine structures, we better understand how the genome guides physiology.
Ph.D. in Biophysics, Massachusetts Institute of Technology, 1964, B.A. in Chemistry, University of Colorado, 1958
Protein Structure Determination
Protein Kinase C (PKC)
3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHPS)